Presented By: Rafael Medina Silva, PhD
Speaker Biography: Dr. Medina is Associate professor in the Department of Pediatric Infectious Diseases and Immunology at the School of Medicine at Pontificia Universidad Catolica de Chile in Santiago.
Webinar: Understanding the Pathogenesis of Human Influenza Virus: A Systems Virology Approach
Webinar Abstract: We evaluated the status of the innate and adaptive immune responses, and established clinical parameters associated with poor outcome. A comprehensive multiscale analysis of clinical metadata and cytokine profiling, revealed that comorbidities such as arterial hypertension, chronic cardiovascular disease and obesity, together with early increased expression of pro-inflammatory cytokines, including of IL-6, 8 and the anti-inflammatory IL-10, were associated with severity.
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