For more information, see Abs et al., Neuron 100/3, [ Ссылка ]30774-8.
How does the brain distinguish between relevant and irrelevant information? Layer 1 of neocortex plays a crucial role in this. In this video, Abs et al. identify NDNF as a specific marker for layer 1 interneurons and show that NDNF interneurons integrate top-down inputs and mediate a prolonged form of dendritic inhibition, which is highly experience dependent.
![](https://s2.save4k.ru/pic/1E1cLE0HT8A/mqdefault.jpg)