Acute Myeloid Leukemia (AML) - Auer Rods - Myeloperoxidase Positive - Hematology.
Acute Myelogenous Leukemia (AML) is a malignant neoplasm (cancer) of myeloid cell lineage (myeloblasts and monoblasts). It's a leukemia (cancer of the blood and the bone marrow). It affects patients between age 40 and age 60 for the most part. Risk factors for AML include Myelodysplastic syndrome (MDS), Benzene, Ionizing radiation exposure, alkylating agents, antineoplastic agents, aplastic anemia, paroxysmal nocturnal hemoglobinuria, and Fanconi anemia. Myeloblasts and/or monoblasts occupy more than 20% of the bone marrow. It can cause anemia, infections, and platelet clots. AML has many subtypes (e.g. M0, M1, M2, M3, M4, M5, M6, and M7). AML is diagnosed by being TdT negative, Myeloperoxidase (MPO) positive, and a hypercellular bone marrow (on bone marrow aspiration/ bone marrow biopsy).
AML = Acute Myeloid Leukemia (or Acute Myelogenous leukemia).
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