Current treatments of MS focus on stopping inflammation, but they do not necessarily address the underlying cause. There is significant evidence that Epstein-Barr Virus (EBV) is part of the causal pathway of MS. ATA188 is an anti-EBV neurogenic t-cell therapy being developed by Atara Biotherapeutics, and in this video, I present their fascinating phase I data.

Selected Sources

ATA188 - Atara Biotherapeutics: [ Ссылка ]
Phase 1/2 Study to Evaluate the Safety and Efficacy of ATA188 in Subjects With Progressive Multiple Sclerosis (EMBOLD): [ Ссылка ]

Tabelecleucel for Solid Organ or Allogeneic Hematopoietic Cell Transplant Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease (EBV+ PTLD) After Failure of Rituximab or Rituximab and Chemotherapy (ALLELE): [ Ссылка ]

A Study to Evaluate Tabelecleucel in Participants With Epstein-barr Virus-associated Diseases: [ Ссылка ]

ECTRIMS presentation: [ Ссылка ]
ATA188 data from Atara: [ Ссылка ]


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My book "Resilience in the Face of Multiple Sclerosis" on Amazon: [ Ссылка ]

Dr. Brandon Beaber is a board-certified neurologist with subspecialty training in multiple sclerosis and other immunological diseases of the nervous system. He is a partner in the Southern California Permanente Medical Group and practices in Downey, California (South Los Angeles). He has several publications on MS epidemiology and has participated in clinical trials for MS therapeutics. You can follow him on twitter @Brandon_Beaber where he regularly posts about MS news and research.

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Music: INNER GRACE - Copyright 2018 Wilton Vought Source: Really Really Free Music Link: [ Ссылка ] T

he video material by Dr. Brandon Beaber is general educational material on health conditions and is not intended to be used by viewers to diagnose or treat any individual's medical condition. Specifically, this material is not a substitute for individualized diagnostic and treatment advice by a qualified medical/health practitioner, licensed in your jurisdiction, who has access to the relevant information available from diagnostic testing, medical interviews, and a physical examination. To the extent that Dr. Beaber endorses any lifestyle change, behavioral intervention, or supplements, the viewer should consult with a qualified healthcare professional to determine the safety and efficacy of the intervention in light of their individualized information.

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