Langerhans cell histiocytosis (LCH) is a cancer-like disease that can occur in any organ of the body.

Infiltration of lesions to the liver, spleen and bone marrow especially can cause serious organ damage

A recent paper by the Institute, reviews our research over 23 years, indicating the major role of immune cells and in particular T cells, in forming lesions in patients with LCH. This includes seminal discoveries, with the identification of a new immune cells subset only seen in LCH lesions

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