The leading causes of blindness and low vision in developed countries are age-related diseases that involve degeneration of retinal cells. Most of the genetic variation associated with age-related retinal degeneration is present in the non-coding genome and predicted to represent regulatory DNA elements. However, the cis-regulatory elements (CREs) that control gene transcription in different retinal cells are poorly understood.

In this webinar, learn how the Swaroop Lab used multi-omics to identify retinal CREs, then used this information to identify principles of retinal genomic regulation and to propose causal genes and variants for common age-related blinding diseases.

During the 1-hour live webinar, you will:

- Learn how integration of high-resolution chromatin conformation data with other epigenomic data sets guides the identification of retina-specific functional DNA elements and principles of gene regulation
- Understand how 3D genomics can contribute to uncover the role of human genetic variation in retinal homeostasis and disease
- Have a chance to ask questions during a live Q&A following the presentation

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