Watch the Full Video at [ Ссылка ].

Microfluidic-based Electrotaxis for On-demand Quantitative Analysis of Caenorhabditis elegans' Locomotion - a 2 minute Preview of the Experimental Protocol

Justin Tong, Pouya Rezai, Sangeena Salam, P. Ravi Selvaganapathy, Bhagwati P. Gupta
McMaster University , Department of Biology; McMaster University , Department of Mechanical Engineering;

A semi-automated micro-electro-fluidic method to induce on-demand locomotion in Caenorhabditis elegans is described. This method is based on the neurophysiologic phenomenon of worms responding to mild electric fields (“electrotaxis”) inside microfluidic channels. Microfluidic electrotaxis serves as a rapid, sensitive, low-cost, and scalable technique to screen for factors affecting neuronal health.

Visit [ Ссылка ] to explore our entire library of 14,000+ videos of laboratory methods and science concepts.

JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching.

Subscribe to our channel: [ Ссылка ]

свернуть