This organic chemistry video tutorial discusses the reaction mechanism of nucleophilic acyl substitution reactions also known as carboxylic acid derivative reactions. This video contains plenty of examples and practice problems.

Here is a list of topics:
1. Acid Chloride Reactions
2. Hydrolysis of Acid Chlorides - Formation of Carboxylic Acids
3. Formation of Esters Using an Acid Chloride and an Alcohol
4. Amide Formation Reactions Using an Amine and an Acid Chloride
5. Tetrahedral Intermediate of Nucleophilic Acyl Substitution Reactions
6. How to predict the major product of a carboxylic acid derivative reaction
7. Acid Catalyzed Ester Hydrolysis Reaction Mechanism
8. Base Promoted Ester Hydrolysis
9. Base Promoted Hydrolysis of Amides
10. Amide Formation Reactions
11. Amide Hydrolysis Reaction Mechanism
12. Ester Formation Reaction Mechanism
13. Lactone Formation Synthesis Reaction
14. Acid Anhydride Formation Reaction Mechanism
15. Amide to Nitrile Mechanism Using SOCl2
16. Dehydration of Amides to Nitriles
17. Lactam Hydrolysis - Cyclic Amides
18. Cyclic Anhydride Formation

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