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Methods for Analyzing the Impacts of Natural Uranium on In Vitro Osteoclastogenesis - a 2 minute Preview of the Experimental Protocol
Tatiana Gritsaenko, Valérie Pierrefite-Carle, Gaëlle Creff, Claude Vidaud, Georges Carle, Sabine Santucci-Darmanin
Université Nice Sophia-Antipolis, UMR E-4320 TIRO-MATOs CEA/DRF/BIAM; Université Nice Sophia-Antipolis, UMR 7272 Institut de Chimie de Nice CNRS; Biosciences and Biotechnologies Institute (BIAM), CEA, Direction de la Recherche Fondamentale (DRF);
Uranium is known to affect bone metabolism. Here, we present a protocol aimed at investigating the effect of natural uranium exposure on the viability, the differentiation, and the function of osteoclasts, the cells in charge of bone resorption.
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