The uveitis treatment typically involves a combination of medications and lifestyle changes. The most common uveitis medications are corticosteroids, which reduce inflammation. These may be given in the form of eye drops, injections, or oral pills. Nonsteroidal anti-inflammatory drugs may also be used to reduce pain and swelling. If the uveitis is caused by an autoimmune disorder, immunosuppressant drugs may be prescribed to reduce the immune system’s activity and prevent further damage to the eye. If the uveitis is caused by an infection, such as bacterial or viral, antibiotics may be recommended.
Gene therapy has the potential to modulate the immune response and reduce inflammation in the eye. EYS606, is a novel non-viral gene therapy approach being developed for treating chronic non infective uveitis. The drug has completed evaluation in Phase two clinical trial.
Stem cell therapy can help reduce inflammation and restore vision by replacing damaged or lost cells in the eye of uveitis patients. Nanoparticle therapy also has the potential to deliver drugs directly to the site of inflammation in the eye of a uveitis patient, improving treatment efficacy and reducing the risk of systemic side effects. Recent studies have shown that photobiomodulation (light therapy) may be effective in treating uveitis and other ocular inflammatory conditions.
Emerging therapies for uveitis treatment are filled with promise in improving treatment outcomes and reducing side effects associated with current therapies. These therapies offer newer possibilities for alternatives or adjuncts to traditional therapies for patients with uveitis.
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