Television
Fantastic Four (1978)
Fantastic Four (1978)
Fantastic Four (1978)
Medusa appeared along with the rest of the Inhumans in one episode and later appeared as a member of the Frightful Four. In this series, she was portrayed as a straight villain with no apparent redeeming qualities. She was voiced by Joan Gerber.

Spider-Man (1981)
Spider-Man (1981)
Spider-Man (1981)
Medusa appeared in the episode Under the Wizard's Spell. She acted as a villain and fought Spider-Man until it was revealed that Medusa was being mind-controlled by the Wizard, who had placed a special collar on her that enslaved her to his will. After the collar was neutralized, the two teamed up to defeat the Wizard. She was voiced by B.J. Ward.

Fantastic Four: The Animated Series (1994-1996)
Fantastic Four (1994)
Fantastic Four (1994)
Medusa appeared in four episodes of the series, mainly in the Inhumans Saga which ran three consecutive episodes. She was initially a member of the Frightful Four and was later revealed to be a member of the Inhumans. The Inhumans were initially hostile to the Fantastic Four until the two sides joined forces against Black Bolt's renegade brother, Maximus the Mad. The show's producer, Tom Tataranowicz, revealed that he wanted to have Medusa join the Fantastic Four during the third season, but unfortunately, the series was canceled after two seasons. Actress Iona Morris provided Medusa's voice in the series.

Hulk and the Agents of S.M.A.S.H. (2013)
Agents of S.M.A.S.H.
Agents of S.M.A.S.H.
Medusa, and the rest of the Inhumans appears in the episode "Inhuman Nature" voiced by Mary Faber.

Guardians of the Galaxy (2016)
Guardians of the Galaxy
Guardians of the Galaxy
Medusa appears in the series, voiced by Mary Faber and later by Rose McGowan. She appears in the episodes "Blue Crystal Persuasion," where she is one of the Inhumans afflicted with a strange condition that causes crystals to grow from their bodies. She is revived by Star-Lord. She returns in "The Inhuman Torch," where she helps the Guardians deal with the escaped Maximus.

Avengers Assemble (2016)
Black Panther's Quest
Black Panther's Quest
Medusa makes her debut in the third season "Marvel's Avengers Ultron Revolution" in the episode "Inhumans Among Us". She returns in the "Civil War" arc near the end of Season 3, where she is initially controlled by Ultron but ultimately helps the Avengers. She returns in Season 5, Black Panther's Quest, where she and Black Bolt greet Black Panther after he arrives in Attilan seeking a piece of a key left behind by his grandfather. She was voiced by Catherine Taber in Season 3, and by Vanessa Marshall in Season 5.

The Inhumans (2017)
Serina Swan as Medusa in Inhumans
Serina Swan as Medusa in Inhumans
Medusa appeared as one of the main characters in the live-action Inhumans TV show. She was portaded by Serinda Swan (known for portraying Zatanna in Smallville).

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