#aminoacyl trna synthetase
#activation site
#editing site
#translation #protein synthesis
#proofreading
#adenylation
#aminoacylatiln
in the second video about protein synthesis, the enzyme Aminoacyl tRNA synthetase is discussed.
1- this ligase links the corresponding amino acid to the tRNA in a 2 step reactions:
a- adenylation of amino acid
b- aminoacylation of tRNA
2- Classes of synthetases
3- structure: it has an activation site and most synthetase have also an editing site for proofreading
4- Proofreading by Aminoacyl-tRNA synthetases increases the fidelity of protein synthesis
5- How do synthetases choose their tRNA partners?
Synthetases interact with the Anticodon Loops and Acceptor Stems of t-RNA and also with various features of tRNA
Links to related video:
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![](https://i.ytimg.com/vi/7tYNTy3X0bY/mqdefault.jpg)