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The ChIP-exo Method: Identifying Protein-DNA Interactions with Near Base Pair Precision - a 2 minute Preview of the Experimental Protocol
Andrea A. Perreault, Bryan J. Venters
Vanderbilt University, Department of Molecular Physiology and Biophysics;
Here, we present a protocol to achieve near base pair resolution of protein-DNA interactions. This is obtained by exonuclease treatment of DNA fragments selectively enriched by chromatin immunoprecipitation (ChIP-exo) followed by high throughput sequencing.
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