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Timestamp and Chapters :
0:00 Introduction
1:08 What is HBA1C test ?
2:05 other names of HBA1C test
2:29 science behind HBA1C test
5:09 where HBA1C test is done ?
5:49 technique used in HBA1C test
6:10 cost and price of HBA1C test
6:45 how HBA1C test is performed ?
8:09 is HBA1C test alternative to regular blood sugar testing ?
10:18 individual target of HBA1C
13:14 benefits and advantages of HBA1C test
16:29 is fasting needed for HBA1C test
17:03 can same blood sample be used for other test ?
17:22 how HBA1C test is interpreted ?
18:22 is it same as regular blood sugar test ?
19:00 indications for HBA1C test
20:23 who all should do the HBA1C test ?
22:47 causes of high HBA1C
24:50 what will happen if HBA1C is high ?
25:18 limitations of HBA1C and factors which can misinterpret HBA1C test
27:48 how frequently HBA1C test to be done ?

It is blood test to detect diabetes. it is recommended by international organizations as WHO and ADA for reliable diagnosis of diabetes.
it is also known as
glycated hemoglobin test, glycohemoglobin, hemoglobin A1C, HbA1c test.
it tells shows average blood sugar over the past 2 to 3 months.
indication
to Diagnose prediabetes.
to diagnose diabetes.
for People who have diabetes
to see if diabetes is within range.
need to adjust your diabetes medicines or not
Monitor diabetes treatment plan and effectiveness of medicine.
Testing for diabetes or prediabetes everyone above 45 years and if you’re under 45
and have risk factors.
Hemoglobin is a protein found in red blood cells.it has alpha and beta chain.
The sugar in your blood is called glucose.
metabolic reaction between hb and glucose happens. glucose binds to beta chain ( n terminal valine ) and forms a stable compound ketoamine
The A1c test measures how much glucose is bound.
because Red blood cells live for about 3 months, so the test shows the average level of glucose in your blood for the past 3 months.
when blood sugars are high and if body cant use them properly, so more of it sticks to your blood cells and builds up in your blood. so % is high
If your glucose levels have been high over recent weeks, your hemoglobin A1c test will be higher.
TECHNIQUE used is HPLC as well as immunoturbidimetric HbA1c assays

ADVANTAGES
No fasting necessary
Sample may be obtained any time of the day
HbA1c is stable in sample material
Not altered by acute factors e.g., stress, exercise
Reflects long-term blood glucose concentration (8-12 weeks)
Single sample
Used to guide treatment
Predicts the development of complications
Get your A1C tested in addition to—not instead of—regular blood sugar test.
Two people can have the same A1C, one with steady blood sugar levels and the other with high and low swings.
CAN IT BE DONE AT HOME
No
IS FASTING NEEDED
It’s not a fasting test. You can take it any time of day, before or after eating.
RESULT INTERPRETATION are in %
causes of high a1c
poorly controlled diabetes
steroid use
physical inactivity
obesity
pcos
cushing
The goal for most people with diabetes is 7% or less.
However, your personal goal will depend on many things such as your age and any other medical conditions.
Work with your doctor to set your own individual A1C goal.
The higher the hemoglobin A1c, the higher your risk of having complications related to diabetes.

what happens if it is high
A high HbA1c means you have too much sugar in your blood. This means you're more likely to develop diabetes complications, like serious problems with your eyes and feet.

limitations and factors Which Can Affect Your A1C
Pregnancy
Recent or heavy blood loss
Recent blood transfusion
anemias and thalassemia
Hemoglobin variants
false misinterpreted with
alcoholism
b12 deficiency
supplements such as vitamins C and E and
high cholesterol levels.

ideally
People with diabetes should check A1c test every 3 months

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Please Note :
This video is for Educational purpose only. We strongly recommend to consult your Doctor/ Physician before taking any medication/Supplementation .
All Contents by Speech & Video by : Dr. Tanvi Mayur Patel
Video Editing, Uploading by : Vimal Vanani, Surat
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