#antibioticresistance #ecoli #infection #antibiotic #microbiology

Antibiotic resistance, when infection-causing bacteria evolve so they are no longer affected by typical antibiotics, is a global concern. New research at the University of Tokyo has mapped the evolution and process of natural selection of Escherichia coli (E. coli) bacteria in the lab. These maps, called fitness landscapes, help us better understand the step-by-step development and characteristics of E. coli resistance to eight different drugs, including antibiotics. Researchers hope their results and methods will be useful for predicting and controlling E. coli and other bacteria in the future.

The researchers used a method called adaptive laboratory evolution, or ALE, to “replay the tape” on the evolution of drug-resistant E. coli to eight different drugs, including antibiotics. The method enabled the researchers to study the evolution of bacterial strains with specific observable characteristics (called phenotypes) in the lab. This helped them gain insight into what changes might occur to the bacteria during the longer-term process of natural selection.

Get the latest medical and health news at medicaldialogues.in
Follow us on
Twitter: [ Ссылка ]
Facebook: [ Ссылка ]
Instagram: [ Ссылка ]
LinkedIn: [ Ссылка ]
Website: [ Ссылка ]

свернуть