An infectious diseases specialist explains HIV testing. What kind of HIV tests are available, how should we use them, and when? How do laboratory-based tests compare to point-of-care HIV tests? What is the sensitivity and specificity of different HIV tests? What is the window period for each test, and how does that influence HIV testing algorithms? What if we want to exclude HIV infection? When should we repeat the test or use another one? How do we approach possible acute HIV infection versus chronic HIV infection or AIDS? As always, this video is primarily intended for clinicians, medical professionals, and students. I highly recommend you follow the links to the research articles I used as resources for this video. You will learn a lot. Good luck!

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DISCLAIMER: Please, always keep in mind that my videos are intended for educational purposes only. The content of my videos is NOT medical advice. I do not practice medicine over the internet. If you are a patient and have any questions about your health, please talk to your doctor.

CHAPTERS:
00:00 What do HIV tests detect?
00:38 The typical progression of HIV infection
01:02 When HIV RNA, p24 antigen, and anti-HIV antibodies become detectable
02:47 HIV testing algorithms, HIV combo tests, confirmatory tests, HIV RNA PCR
05:44 Point-of-care HIV tests
07:02 Window periods for different HIV tests (HIV RNA PCR, HIV combo tests, HIV antibody tests): What do they really mean?

REFERENCES & RECOMMENDED READING:
1. Hoffmann C, Rockstroh JK. HIV 2015/2016 [Internet]. 2015 [cited 2022 May 10]. Available from: [ Ссылка ]
2. HIV Testing Window Period | From Denver PTC | denverptc.org [Internet]. [cited 2022 May 10]. Available from: [ Ссылка ]
3. HURT CB, NELSON JAE, HIGHTOW-WEIDMAN LB, MILLER WC. Selecting an HIV Test: A Narrative Review for Clinicians and Researchers. Sex Transm Dis. 2017 Dec;44(12):739–46.

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