Parkinson’s disease (PD) is the second most common neurodegenerative disease after Alzheimer’s. Although the pathogenesis of PD remains largely uncertain, a variety of mechanisms have been proposed – one of which implicates the role of inflammation in the progression of the disease. But how much do we currently know about the link between inflammation and PD? Are these inflammatory processes directly involved in the etiology of PD, or are they a consequence of the disease?
In this video, Dr Nicole Polinksi from the Michael J Fox Foundation for Parkinson’s Research (NY, USA) discusses the Foundation’s efforts to understand the role of neuroinflammation in PD and investigates the utility of neuroinflammatory readouts for biomarker development for PD. Dr Polinski is also joined by Dr Elnaz Atabakhsh from Abcam (MA, USA), who presents data utilizing the FirePlex® platform for multiplex quantitation of neuroinflammatory biomarkers in PD patient samples.
