Dr. Gllava reviews the value of the procalcitonin laboratory test as an inflammatory marker useful in making treatment decisions in infectious diseases patients. First, she introduces the idea of a biomarker: a laboratory assay that is useful in detecting inflammatory states. She then explains the advantages and disadvantages of procalcitonin as an ideal biomarker. Dr. Gllava goes on to describe the current recommendations for the use of procalcitonin in specific infectious conditions and reviews the body of scientific evidence for its use. Lastly, she reviews how hospitals can utilize procalcitonin-based algorithms to improve clinical care and promote antimicrobial stewardship.
