A prediabetic could still have a relatively “normal” blood glucose response in the Oral Glucose Tolerance Test. They could also be near the upper end of fasting glucose and hemoglobin A1c.
The Kraft Test measures your glucose and insulin response 30 minutes, 1, 2, and 3 hours after consuming 75 grams of glucose.
In people with a healthy insulin response, you should see the insulin curve following the blood glucose curve.
But in someone who has prediabetes, the insulin curve will be higher because more insulin is needed. This is because the cells are less sensitive to insulin’s effect. Their body is a little insulin resistant, but their insulin can still keep up and that brings the sugar level down.
But eventually their body won’t be able to make enough insulin to keep up and they will have impaired fasting glucose - or prediabetes. Left untreated, prediabetes can develop into type 2 diabetes with both elevated glucose and insulin levels.
This 2017 research study backs this claim up and says that:
“Using fasting glucose, oral glucose tolerance test (OGTT) or A1c may not be the most effective early screening tool for T2D.”
“Incorporating fasting insulin and especially insulin after an oral glucose tolerance test as enhanced screening methods, may help to increase the ability to detect diabetes and prediabetes, allowing earlier intervention to prevent diabetic complications.”
Source: Postprandial insulin assay as the earliest biomarker for diagnosing pre-diabetes, type 2 diabetes and increased cardiovascular risk: [ Ссылка ]
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Dr. Morgan Nolte is a doctor of physical therapy and a board-certified clinical specialist in geriatric physical therapy. This video is for general informational purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, and prescription or recommendation. It does not create a doctor-patient relationship between Dr. Nolte and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Zivli, LLC and Morgan Nolte, PT, DPT are not liable or responsible for any advice, course of treatment, diagnosis or any conclusions drawn, services or product you obtain through this video or site.
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