Dr. Rajsree Nambudripad, MD is board-certified in Internal Medicine and founder of OC Integrative Medicine in Fullerton, California. In this video, Dr. Rajsree explains the science of aging and all the factors that affect your longevity, from genetics, to diet, exercise, exposures, and lifestyle. What's the difference between Lifespan and Healthspan? Biological Age vs. Chronological Age? What are the hallmarks of aging? Learn about Sirtuins, AMKP, and mTOR, and Autophagy and how they impact your longevity. How does the gut microbiome impact your Longevity? How does chronic inflammation affect Longevity? She reviews the latest science on Diet, Lifestyle, and Supplements to promote health and longevity.
00:00 Introduction
00:42 Lifespan vs. Healthspan
01:31 Outward Signs of Aging
01:57 Proactive and Preventative Approach to Health and Longevity
02:20 Key Lab Biomarkers
03:45 Chronological Age vs. Biological Age
04:18 Supercentenarians
04:31 Factor Influencing Longevity
05:03 Hallmarks of Aging
08:23 Epigenetic Clock
08:59 Sirtuins, AMPK, and mTOR
13:30 Autophagy
14:58 Time Restricted Eating
16:00 Gut Microbiome and Longevity
17:19 Inflammation and Longevity
17:48 Inflammaging
18:43 Sugar and Advanced Glycation Endproducts
20:18 David Sinclair, PhD and Information Theory of Aging
20:48 Yamanaka Genes (Fountain of Youth Genes)
21:14 The Future: Gene Therapy and Senolytics
22:22 Blue Zones
23:47 Diet: Key Principles
25:35 Intermittent Fasting
26:31 Exercise
27:20 Hormesis
28:09 Supplements to Improve Your Healthspan
29:53 Berberine for Insulin Resistance
30:42 Sleep
31:02 Minimize Exposure to Toxins
31:44 Relationships with People
32:17 Case Example: Mike
32:40 Key Points
➡️Watch Dr. Rajsree's video on Autophagy:
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➡️ Watch Dr. Rajsree's video on Insulin Resistance (Paleo Diet):
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➡️ Watch Dr. Rajsree's video on Clean Keto Diet:
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🧡 Shop for Supplements by Dr. Rajsree:
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This information, including but not limited to, text, graphics, images and other material contained on this video and website are for informational and educational purposes only. No material in this video is intended to be a substitute for professional medical advice, diagnosis, treatment, or medical supplement approved by the Food and Drug Administration. The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician. Never disregard professional medical advice or delay in seeking it because of something you have seen in this video. No physician-patient relationship is created by this video or the information provided. Furthermore, neither Rajsree Nambudripad, MD or any contributor to this video, makes any representations, express or implied, with respect to the information provided herein or to its use.
