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Glomerular filtration rate
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Description: the rate at which fluid is filtered by the kidneys
Normal GFR
♂ 95–145 mL/min/1.73m2
♀ 75–125 mL/min/1.73m2
The GFR physiologically declines with age.
GFR depends on the effective filtration pressure and is driven by the difference between hydrostatic and osmotic pressure
EFP = (PGC – PBS) – (πGC – πBS)]
GC = glomerular capillary
BS = Bowman space
P = hydrostatic pressure
π = osmotic pressure
πBS normally equals 0
Normal effective filtration pressure is 13 mm Hg
Starling equation for the glomerulus: Jv = Kf × [(PGC - PBS) - σ(πGC - πBS)]
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Glomerular filtration rate - Usmle Renal Physiology Animations
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