This paper looks at a mouse study with alpha ketoglutarate which was run by the Buck Institute in the Lightgow Lab. The study looked at the effects of AKG when fed to middle aged mice in their food. The out comes that they looked for were lifespan and frailty. We are reviewing this paper to provide some background to our upcoming interview with Dr. Lithgow.
The paper is here
Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice
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