GLP-1 RAs are associated with a number of multifactorial effects, including reduction in weight, protection against cardiovascular events, and improvements in HbA1c. Given their indications in type 2 diabetes, this class of agents can be particularly suited to helping specific patient presentations. But how do they work?

This 5-minute video, steered by Carel le Roux, examines the mechanism of action of GLP-1 RAs, including their effects on glucose, cardiovascular disease, and the neurohormonal system. It also discusses injectable and oral formations and strategies for discussing the therapeutic class with your patients to help them overcome fears and understand the benefits of this treatment.

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