We continue the beginner-friendly lecture series introducing basic concepts in #genomics, with a focus on single nucleotide polymorphism (#SNP) data. In this part, we talk about the concept of haplotypes, including an optional short pen and paper exercise to identify haplotype combinations. As a follow-up, we talk about the basic theory behind the genomic #imputation including the possibilities behind it. The imputation of sporadically missing SNPs is explained, as well as imputation from lower to higher density SNP chips.
Playlist with the full videos: [ Ссылка ]
All PowerPoint presentations are available at: [ Ссылка ]
Parts of the video:
0:00 - Summary from previous lectures
0:48 - Haplotypes
5:07 - Phasing
7:16 - Imputation - general definition
8:22 - Imputation of sporadically missing genotypes
9:40 - Imputation between different SNP densities
13:12 - Imputation accuracy and practical use
17:28 - Summary of the lecture
Image source in thumbnail: [ Ссылка ]
Support the channel
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To support the Genomics Boot Camp channel, check out the associated site for genotyping services covering companion animals, livestock and more: [ Ссылка ]
