C1INH
Key Concepts
1. C1INH (C1 inhibitor) inhibits the formation of bradykinin, a potent vasoactive peptide responsible for edema formation.
2. Inhibits the classical pathway by removing Cr and Cs from C1 complex.
3. Inhibits the lectin pathway by removing MASP-1 and -2 from MBL complex.
4. Soluble complement regulatory protein
00:11 - Functions of C1INH
00:51 - C1INH Inhibits classical pathway
00:51 - C1INH Inhibits formation of bradikins
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