In the first couple hours of the game you are limited in what you are capable of doing. One of the main things is applying status effects to enemies. You cant fill your rage easily either because you cant use the Yggdrasil Gateways. So in the early game using this setup is best. During the early parts of the game I use the full Zeus set and only swap it for the Berserker chest piece for bosses. If you ever see me not at full health its due to the changing of the chest piece.
When fighting story bosses the game limits how much damage you can do since they want you to fight the boss in multiple stages. After each stage you can reset your cooldowns by using the Restart Checkpoint feature. However when doing this wait until you are able to move Kratos. If you don't wait that long you will restart back to the boss stage you just did.
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