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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that was originally developed for the treatment of type 2 diabetes. GLP-1 is a hormone produced in the intestines that increases insulin secretion, reduces glucagon secretion (a hormone that raises blood sugar), slows gastric emptying, and reduces appetite. GLP-1 receptor agonists, like semaglutide, mimic the effects of the natural hormone, leading to various beneficial effects in people with type 2 diabetes.
In addition to its effects on blood sugar control, semaglutide, like other GLP-1 receptor agonists, has been noted to cause weight loss in many patients. This effect is believed to be primarily due to its appetite-suppressing properties. Given the weight loss effect, researchers began investigating the potential of semaglutide as a treatment for obesity.
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