Abstract: Lichen planus is an inflammatory mucocutaneous disease of unknown pathogenesis with a prevalence of 0.5--2%. Most patients are middle-aged or elderly women.
Esophageal involvement seems to be high (50%), but the great majority of patients do not show any symptoms. Endoscopic findings include lacy white papules or submucosal plaques, peeling tissue paper-like pseudomembranes, hyperemic lesions, erosive changes, ulceration, and stenosis.
Owing to missing data there are no evidence-based therapeutic recommendations. Probatory therapeutic regimes with use of acute flares of systemic corticosteroids, immunosuppressants, rituximab, and topical corticosteroids have shown positive effects. In case of esophageal stenosis, bougienage is required. Malignant transformation has been reported in rare cases. This article is part of an expert video encyclopedia.
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