Is there a difference in biomarkers of smoke exposure between reducing nicotine content of cigarettes immediately vs gradually? This JAMA video abstract summarizes a randomized trial that compares the effects of immediate vs gradual vs no reduction in nicotine content on breath carbon monoxide (CO) measures and other biomarkers of cigarette smoke exposure. Read the JAMA study here: [ Ссылка ]. JAMA Network Open study: [ Ссылка ]

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