Gene editing may not be the safest HIV cure strategy, early findings warn
Findings only apply to CRISPR/Cas9 gene editing
Gene editing with CRISPR/Cas9 can lead to unwanted ‘cuts’ and changes in the gene sequences near to the integrated HIV genes, Dutch researchers report in the Journal of Virology. This might activate host genes that could contribute to cancer development, raising concerns about this potential HIV cure strategy.

Gene editing technologies are expected to revolutionise modern medicine and treatment approaches for many diseases. There are currently several strategies for a potential HIV cure, including gene editing, which is thought to have the potential to permanently remove the virus from most or all bodily cells. Another possibility would be introducing new or modified genes in our cells that make them resistant to the virus. However, there are risks associated with any intervention dealing with our genes.
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