Shannen Doherty has died after years of living with cancer, PEOPLE has confirmed. She was 53.

"It is with a heavy heart that I confirm the passing of actress Shannen Doherty. On Saturday, July 13, she lost her battle with cancer after many years of fighting the disease," Doherty's longtime publicist Leslie Sloane confirmed in an exclusive statement to PEOPLE on Sunday, July 14.

"The devoted daughter, sister, aunt and friend was surrounded by her loved ones as well as her dog, Bowie. The family asks for their privacy at this time so they can grieve in peace," Sloane continued.

The Beverly Hills 90210 star was first diagnosed with breast cancer in 2015 and spoke candidly to PEOPLE in November 2023 about her Stage 4 breast cancer, which had by then spread to her bones, saying at the time that she didn't "want to die."

“I’m not done with living. I’m not done with loving. I’m not done with creating. I’m not done with hopefully changing things for the better,” she told PEOPLE. "I’m just not — I’m not done.”

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