Vipul Sheth, PhD, Fred Hutchinson Cancer Research Center, Seattle, USA, comments on the management of cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS) after chimeric-antigen receptor T-cell (CAR-T) therapy for patients with acute lymphoblastic leukemia (ALL). This interview took place at the virtual European Hematology Association (EHA) Congress 2021.

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