Striatech hosts a series of online journal clubs, highlighting the use and the applications of our OptoDrum device. Scientists present their projects and new data, and you can learn about the latest developments in the field. There is always a Q&A session at the end.

Topic: Measuring Visual Acuity and Contrast Sensitivity by Optomotor Reflex in Rodents
Speaker:
Dr. Kaushikaram Subramanian - Max Planck Institute of Molecular Cell Biology and Genetics
Prof. Volker Enzmann - Department of Ophthalmology, University of Bern
Dr. Thomas Münch - Striatech

Description:
There is a growing need for behavioral readouts to monitor disease progression and to assess the success of a potential therapy. In vision research, observing the optomotor reflex (OMR) is an important and widely established method for assessing visual acuity and contrast sensitivity in rodents. These tests can be performed with freely moving animals without any need for anesthesia or restraints. In addition, since OMR is a reflex-based behavior, observing it does not require any training of the animal.
Prof. Volker Enzmann from the University Hospital Bern discusses the pros and cons of using OMR measurements as a readout tool for visual performance in mouse models of retinal degeneration. In addition, he shares data from his research on multiple sclerosis, laser treatment and treatment with sodium iodate.
Dr. Kaushikaram Subramanian from the Max Planck Institute of Molecular Cell Biology & Genetics in Dresden explains how chromatin architecture affects light scattering by photoreceptor nuclei. Following, he shows how the chromatin architecture found in night-active animals provides a visual advantage under scotopic conditions.

Visit Striatech's website to learn more: [ Ссылка ]

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