In this episode, we delve into the world of micro-dosing psychedelics, with a particular focus on understanding the potential risks involved. Join us as Dr. Kelan Thomas sheds light on the adverse effects of psychedelics, emphasizing the importance of caution and awareness, especially in the realm of microdosing LSD and psilocybin.

Dr. Thomas provides valuable insights into the binding affinities of psychedelic compounds and their intricate effects on serotonin receptors, including the 5-HT2B receptor. With a keen focus on mental health and psychedelic therapy, this discussion uncovers essential considerations for anyone exploring the realm of microdosing.

Tune in to gain a deeper understanding of microdosing, psychedelic therapy, and the nuanced risks associated with these transformative substances.

Video Chapters:
00:00 Introduction
07:35 Kelan Thomas's Background and Expertise
12:10 Understanding Serotonin Receptors and Binding Affinities
20:40 Valvular Heart Disease and Risks of Chronic Microdosing
29:50 Responsible Use and Research
36:20 Linking SSRIs and Psychedelics
44:10 Potential Heart Health Risks of Microdosing
51:50 Discussion on adverse effects of psychedelics


Key Topics Explored:
- How has Dr. Kelan Thomas contributed to improving mental health care through clinical pharmacy and research?
- What are the potential risks of chronic microdosing of serotonergic psychedelics?
- What is the significance of the 5-HT2B receptor in relation to the potential heart risks associated with microdosing?
- What evidence exists regarding the safety of mixing SSRIs and psychedelics?
- What are the implications of the FDA regulatory reviews on valvular heart disease risk?
- What are the effects of psychedelic compounds on serotonin receptors and their mechanisms of action?
- How does Dr. Kelan Thomas emphasize responsible use and the need for understanding the effects and risks of various substances?


Catch the full audio episode only in the Mind, Body, Health, and Politics Podcast.

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Psychedelic Medicine: The Healing Powers of LSD, MDMA, Psilocybin, and Ayahuasca: [ Ссылка ]
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