What is whole exome sequencing? What is importance of whole exome sequencing?
▶️ If your mutation type is nonsense, please join us: [ Ссылка ]
▶️ If you uncertain what is your mutation type, follow the instructions on our website: [ Ссылка ]
Hello Guys! Welcome and in this video we will discuss about whole exome sequencing test, and the importance of picking up the data files.
If you or your kid went through a whole exome sequencing test, were you aware of the importance of picking up the data files? Even if you haven't done it right away, in most cases you can still get your data files.
Whole-exome sequencing is a popular next-generation sequencing (NGS) approach for sequencing the genome's protein-coding regions. The human exome makes up less than 2% of the genome but contains 85% of known disease-related variants1, making it a more cost-effective method than whole-genome sequencing.
Exome enrichment and exome sequencing can be used to quickly detect coding variants in a variety of applications, including population genetics, genetic illness, and cancer research.
▶️ Advantages of Exome Sequencing:
• Variants are detected across a wide range of applications.
• Ensures that all coding regions are covered.
• Exome sequencing is a less expensive alternative to whole-genome sequencing (4–5 Gb per exome vs. 90 Gb per full human genome).
• When compared to whole-genome techniques, produces a smaller, more manageable data collection for faster, easier data analysis.
▶️ Efficient Analysis of Coding Regions
When whole-genome sequencing is neither feasible or essential, exome sequencing provides a cost-effective alternative. Only sequencing the coding portions of the genome allows researchers to concentrate their efforts on the genes that are most likely to influence phenotype, while also providing an affordable mix of turnaround time and cost.
Exome sequencing detects variations in coding exons and can be expanded to include untranslated regions (UTRs) and microRNA for a more complete picture of gene regulation. DNA libraries can be made in as little as one day, and each exome only requires 4–5 GB of sequencing space.
So, watch till the end and you can share your thoughts in the comments.
If you like the video, Please SUBSCRIBE and don’t forget to press the bell, 🔔 like, comment and share the video. Stay safe and Love all. 😍😘
-------------
▶️ Please subscribe: [ Ссылка ]
-------------
▶️ Visit us: [ Ссылка ]
-------------
▶️ Follow us on Facebook: [ Ссылка ]
-------------
▶️ For business enquiries: info@nonsenseMutations.com
-------------
▶️ Other video:
• Introduction to Genetic Disorders: [ Ссылка ]
-------------
▶️ Music Credits:
• Papanan Kasettretat - "Inspirational Pop Music"
• Licensed under Creative Commons: By Attribution 3.0 Unported
• [ Ссылка ]
-------------
#wholeexomesequencing #NonsenseMutationFoundation #wholegenomesequencing #nonsensemutations #exomesequencing #genetictesting #geneticdisorders #geneticdiseases #genetics

свернуть