Consulting detective Sherlock Holmes fakes his own death in Scotland in order to investigate a number of bizarre apparent suicides that he is convinced are part of an elaborate plot by "a female Moriarty". Returning to his assistant Watson in secret, Holmes notes that all the victims were wealthy gamblers, so disguised as "Rajni Singh", a distinguished Indian officer, he stalks London's gaming clubs.
It is not long before he encounters the archvillain, Adrea Spedding. Holmes discovers that she seeks out men short of money, persuades them to pawn their life insurance policies with her accomplices, then kills them. Holmes sets himself up as her next victim, discovering that she uses the deadly spider, Lycosa Carnivora, whose venom causes such excruciating pain that the victims kill themselves. Holmes also finds the footprint of a child nearby.
Searching for evidence Holmes and Watson visit eminent arachnologist Matthew Ordway, who may have supplied the deadly creatures. Holmes soon realizes that the man he is speaking to is an impostor, but the man makes his escape. Searching the premises, Holmes finds the corpse of the real Ordway, as well as his journals, which allude to something or someone from Central Africa immune to the spider venom. This baffles Holmes until he finds the model skeleton of a child. However, Dr. Watson points out that the relation of the skull and the circumference of the chest prove it is not a child, and Holmes deduces that the Central African thing described in the journal is a pygmy.
Holmes and Watson continue their investigations at a nearby fairground, where Holmes allows himself to fall into the clutches of Spedding and her gang. Bound and gagged, Holmes is tied behind a moving target in a shooting gallery, at which Lestrade and Watson take pot shots with a .22 rifle. However Holmes manages to escape, and Lestrade and the police arrest Spedding, her gang, and the pygmy.
CAST
Basil Rathbone as Sherlock Holmes
Nigel Bruce as Dr. John Watson
Gale Sondergaard as Adrea Spedding
Vernon Downing as Norman Locke
Dennis Hoey as Inspector Lestrade
Alec Craig as Radlik
Arthur Hohl as Adam Gilflower
Mary Gordon as Mrs. Hudson
Teddy Infuhr as Larry
Angelo Rossitto as The Pygmy
Harry Cording as Fred Garvin (uncredited)
Robert Milasch as Carnival Barker (uncredited)
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