Beam Therapeutics announced this week of their first allogenic CAR-T base editing development candidate, BEAM-201, so i thought i would check out their data!
Here i discuss the concept of base editing and how it is being used by Beam Therapeutics for their therapy BEAM-201, whereby they induce 4 simultaneous gene edits in T-cells that can be used in CAR-T therapy for the treatment of T-ALL (T-cell acute lymphoblastic leukemia). The edits enable the T-cells to be universally used.
#baseediting #beamtherapeutics
TIMESTAMPS;
Intro - 00:00
Beam Therapeutics - 01:00
Base editing - 01:40
BEAM-201- 05:40
CAR-T cells - 06:00
4 gene edits- 07:40
Preclinical results- 09:40
Links
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