This channel is linked to the GABAA receptor. The opening of the chloride channel causes hyperpolarisation. Drugs like benzodiazepines, barbiturates, alcohol, neuro-active steroids act through Chloride Channel opening. It has a role in anxiety, muscle relaxation, epilepsy, sedation etc.
#pharmacy, #pharmacology, #clinicalpharmacology , #cellularandmolecularpharmacology, #pharmacotherapeutics, #biochemistry, #pharmacokinetics, #pharmacodynamics, #pathophysiology.
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