A new retrospective study of seven patients diagnosed with monkeypox in the UK between 2018 and 2021, suggests that some antiviral medications might have the potential to shorten symptoms and reduce the amount of time a patient is contagious. The cases analysed in the study, published in The Lancet Infectious Diseases journal, represent the first instances of in-hospital transmission and household transmission outside of Africa, as well as reporting the patient response to the first off-label use of two different antiviral medications – brincidofovir and tecovirimat – to treat the disease.
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