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Gladstone and UCSF leaders celebrated news of the Nobel Prize for Yamanaka, MD, PhD, a senior investigator at the UCSF-affiliated Gladstone Institutes and a UCSF professor of anatomy, who discovered a way to reprogram ordinary human skin cells into stem cells that could be used to grow tissues for organ transplantation and for other medical applications. His discovery came nearly 50 years after John Gurdon, PhD, of the Gurdon Institute in Cambridge, England -- with whom Yamanaka shares the Nobel Prize -- showed in frogs that the genetic program of a mature cell could be "reset" to its embryonic state.

The stem cell discovery by Shinya Yamanaka that won the 2012 Nobel Prize in Medicine not only has transformed the research landscape, but it has revolutionized medicine over the coming decade, colleagues at the Gladstone Institutes and UCSF say.

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