Dr. John McCafferty, IONTAS, UK
Equine polyclonal antibodies such as “EchiTab-plus-ICP”, used in sub-Saharan Africa save lives of snakebite victims. This century-old approach however requires injection of grams of an ill-defined, variable mix of non-human protein to snakebite victims. There is an opportunity in revolutionising anti-venom treatment by using recombinant antibody technology to identify and combine the active components from polyclonal antivenom responses. This presentation will review the opportunities and challenges.
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