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We NEED Zinc, Magnesium, Vitamin D & Vitamin C for Our Immune System Health- Thomas DeLauer
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Immune cells need vitamin C, but without vitamin D T cells remain dormant. However, taking vitamin D will deplete magnesium stores. Zinc also has a positive influence on the immune system, as does copper.Iron does have a role in immune system function, but you cannot excrete excess, which can cause damage to organs, and it competes with magnesium for oxygen. So, in theory, taking too much iron could reduce magnesium, which could then render vitamin D useless, which would ultimately mean taking vitamin C would be pointless in regards to T cells as they wouldn't be able to activate and utilize vitamin C.

Vitamin C

Immune cells have active vitamin C transporter molecules embedded in their membranes that actively pump the vitamin into the cells when more vitamin C is required

Vitamin C produces beneficial effects on virtually all of the immune system’s cells

Study - Nutrients

In 2014, a study of vitamin C published in the journal Nutrients found that vitamin C supplementation can reduce the incidence of the common cold in otherwise healthy people with chronic stress or obesity

During the study, 85% of placebo recipients experienced a cold compared with just 47% of supplemented subjects

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Vitamin D

When a T cell is exposed to a foreign pathogen, it extends a signaling device (vitamin D receptor) with which it searches for vitamin D

This means that the T cell must have vitamin D or activation of the cell will cease - if the T cells cannot find enough vitamin D in the blood, they won't activate

Vitamin C Needed to Convert Vitamin D into its Active Form

A study published in the Journal of Nutrition revealed that Vitamin C plays a critical role in Vitamin D metabolism

It was found that while Vitamin C deficiency “potentiated effects of Vitamin D deprivation and impaired a restorative action of Vitamin D”

Vitamin C has been shown to specifically to influence the activity of 25(OH)D3-1-hydroxylase, the enzyme responsible for the transformation of 25(OH)D3 to 1,25(OH)2D3 (active form of D3)

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Magnesium

A review published in The Journal of the American Osteopathic Association found Vitamin D can't be metabolized without sufficient magnesium levels

Magnesium is involved in hundreds of biological reactions, including the enzymes that play a role in vitamin D metabolism - vitamin D can't be converted into its active form, calcitriol, without sufficient amounts of magnesium

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Zinc

When a pathogen is recognized, NF-κB is activated and enters the nucleus, a gene is expressed that produces a zinc transporter called ZIP8

After cell entry, zinc is then directed to and binds to a different protein in the NF-κB pathway - when this happens, it halts any further activity in that process
In other words, zinc helps prevent excess inflammation

It’s essentially a feedback loop, stopping the process getting out of hand

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Fasting Guides
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