A recent clinical trial at GOSH means that 13-yr-old Alyssa is the first person in the world to receive base-edited therapy as part of her leukaemia treatment.

But what exactly is base editing? And how could it help more children like Alyssa? Our handy animation explains.

Illustrated by Dr Maryam Clark (as part of an NIHR GOSH BRC Research Communications Internship), edited by Maisie Hardy.

Learn more about this research breakthrough on our website: To learn more about this research breakthrough, visit our website:
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