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Peter J. Gruber, MD, PhD, is a pediatric cardiothoracic surgeon who treats patients from infancy—in some cases before they are born—to adults. He specializes in complex congenital heart disease, also known as structural heart disease, and performs a wide spectrum of procedures and complex surgeries, including pediatric heart transplant.
A professor of surgery at Yale School of Medicine, Dr. Gruber has training as a developmental biologist and a geneticist, and he has a special interest in the molecular underpinnings of congenital heart disease. This work has impacted his work in the clinic as well. He had a patient with Wolff-Parkinson-White syndrome, characterized by abnormal electrical pathways in the heart, who needed a complex reconstruction inside of her heart. After the surgery, she developed an unusual irregular heartbeat, and she told Dr. Gruber that other members of her family had experienced the same thing. So, his research group sequenced and examined their DNA.
