For International HPV Awareness Day, two Kirby Institute researchers spoke about the innovative strategies being used to prevent HPV in low- and middle-income countries.
Kirby Institute Seminar Series – 2 March 2021
In 2018, 311,000 women died from cervical cancer, with most of these deaths occurring in low- and middle-income countries. WHO's Global Strategy to Accelerate the Elimination of Cervical Cancer as a public health problem, outlines three key steps: human papillomavirus (HPV) vaccination, cervical screening and early treatment. Successful global implementation of all three interventions is predicted to reduce more than 40% of new cases of the disease and 5 million related deaths by 2050.
For International HPV Awareness Day, we’ll be hearing from two Kirby Institute researchers working on innovative strategies to improve uptake of these highly effective preventions in settings with the highest disease burden; Dr Dorothy Machalek, who is investigating the impact of a single-dose HPV vaccine, and Professor Andrew Vallely, who is working on simple and accessible strategies for the early detection and treatment of cervical disease.
0:00 Webinar welcome
0:44 Introducing Dr Dorothy Machalek
1:47 Dr Machalek on HPV vaccination for the prevention of PV and cervical cancer
30:54 Introducing Professor Andrew Vallely
32:20 Professor Vallely on point-of-care testing and treatment for cervical screening in low- and middle-income countries
53:03 Q&A
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Dr Dorothy Machalek
Senior Research Fellow, Public Health Interventions Research Program, Kirby Institute
Dorothy Machalek is a public health epidemiologist and Senior Research Fellow. She holds a Doctorate in epidemiology and a Master of Public Health from the University of New South Wales. Her research focuses on improving control of HPV, the primary cause of cervical cancer, which is the fourth-most common malignancy in women globally. Dr Machalek leads a National HPV Monitoring Program funded by the Commonwealth Department of Health. The program is evaluating the impact of Australia’s HPV vaccination program by tracking changes in HPV infection prevalence over time in different populations. She is also a Chief Investigator on a world-first project that is measuring the impact of one and two-dose HPV vaccine schedules in South Africa, co-funded by the NHMRC and the Bill and Melinda Gates Foundation.
Professor Andrew Vallely
Professor, Public Health Interventions Research Program, Kirby Institute
Andrew Vallely is a clinical epidemiologist with over 20 years’ experience in international public health, HIV/STI and infectious disease interventions research. Andrew has designed and led multi-disciplinary research teams in Australia, Kenya, Papua New Guinea, Solomon Islands, Tanzania, United Kingdom and Vanuatu. He has held a joint appointment with the Papua New Guinea Institute of Medical Research (PNGIMR) since 2010, where he jointly established and led a new Sexual and Reproductive Health Unit, and was Deputy Director from 2010-15. His collaborative research group recently completed two large-scale field trials involving over 5000 women in PNG that evaluated the clinical performance, cost-effectiveness, health system implementation requirements, and acceptability of point-of-care HPV testing and same-day treatment for cervical screening in high-burden, low-resource settings.
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Opinions expressed in the Kirby Institute Seminar Series are solely those of the speaker and do not necessarily represent the views or opinions of the Kirby Institute or UNSW.
