Presented By: F.J. . Voskuil, MD, PhD
Speaker Biography: Floris Jan Voskuil was born on September 10th, 1991, in Nieuwegein, the Netherlands. During his study Medicine at the University of Groningen, Floris was actively involved in several extracurricular organizing committees. After obtaining his Bachelor’s degree, Floris performed his Master’s research thesis at the Brigham and Women’s Hospital, Harvard Medical School, Boston, USA, where he investigated the role of an anti-cancer drug on the vascular endothelium under supervision of prof. Garcia-Cardeña. Once returned, he performed his clinical internships at the Wilhelmina Hospital, Assen and the Isala Hospital, Zwolle. Here, the interest in surgical oncology started. In 2017, after doing his final internships at the departments of Surgery and Plastic Surgery in the Martini Hospital, Groningen, he finished his Master’s degree. He graduated with distinction. Supervised by prof. dr. M.J.H. Witjes, prof. dr. G.M. van Dam and prof. dr. W.B. Nagengast, Floris started as PhD-candidate, investigating optical imaging techniques for the enhanced detection of solid tumors at the University Medical Center Groningen. Floris presented his study results at several international congresses and was awarded with the ‘Young Investigator Award Finalist’ and the ‘BOOA research grant’ among others. In March 2021, Floris obtained his PhD degree with distinction with his thesis: “Clinical application of near infrared fluorescence imaging in solid cancer - Improving surgical accuracy by lighting up tumors”. Currently he is appointed as a postdoc at the department of Oral & Maxillofacial Surgery at the University Medical Center Groningen. The Univerisity Medical Center Groningen has recently awarded him with the prestigious Mandema Stipend, a personal grant which will allow him to set up his own research line. He will start in 2023 with his residency at the same department, after finishing his Master in Dentistry.
Webinar: Fluorescence molecular imaging in head and neck cancer patients
Webinar Abstract: In oral cancer surgery, the ultimate goal is to obtain tumor-negative resection margins. Yet, tumor-positive resection margins occur in up to 43% of the patients, and is associated with disease-specific death. Currently, no tools are clinically available to guide the surgeon in obtaining a complete resection. Phase I studies have shown the potential of Fluorescence Molecular Imaging (FMI) for intraoperative margin assessment, although studies that determine its clinical value are lacking. In this presentation, the author will reflect on two clinical trials performed at the University Medical Center Groningen (phase I-II), in which FMI was investigated in oral cancer patients. Both the results of an antibody-based and a pH-sensitive fluorescent imaging agent will be discussed.
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