Mark Levis, MD, PhD, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, shares the results of the BTM-CTN 1506 (MORPHO; NCT02997202) Phase III study evaluating gilteritinib as a post-transplant maintenance therapy for patients with acute myeloid leukemia (AML) carrying an internal tandem duplication mutation of FLT3 (FLT3-ITD). Whilst the study did not show a benefit for gilteritinib in all patients, its positive effect was more pronounced in patients who were measurable residual disease (MRD)-positive before allogeneic transplantation. This interview took place at the 28th Congress of the European Hematology Association (EHA) 2023 in Frankfurt, Germany.
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