0:00 - Introduction
00:44- How do mRNA Covid vaccines work?
02:21- History of mRNA vaccines
02:48- Advantages of covid-19 vaccines over other vaccines
04:32- Effectiveness of mRNA vaccines for the new Covid variant
06:01- Is mRNA manipulation the holy grail for other diseases?
07:39- Correlation of blood types with covid-19 susceptibility, morbidity and mortality.
08:44- Adaptability of covid-19 vaccine for future covid variants
11:12- Side effects of the second dose of covid vaccine
12:39- Effect of second dose on the immune system
14:48- Are mRNA vaccines less effective on cancer patients, specifically blood cancer patients?
16:29- Effectiveness of covid vaccine in cancer patients
18:04- Is it the cancer treatment or the genetics of the cancer itself that's making covid vaccines less effective?
19:13- What should vaccinated cancer patients be careful about?
21:33- What to infer if there is zero response to the vaccine shot?
22:26- Duration of action of the immune response of mRNA vaccines
23:58- Possibility of development of Pan-Coronavirus vaccine
26:13- mRNA technology and future of cancer vaccines
28:15- Which is most likely to be successful-Car T cells, bi-specific antibodies or vaccines?
29:31- Differences in antibody repertoire between mRNA vaccines and attenuated virus vaccines
31:39- Why is a booster dose needed for mRNA vaccines?
34:28- Basic roles of mRNA and DNA
36:08- Ongoing covid-19 vaccine clinical trials
Messenger RNA vaccines, also called mRNA vaccines, are some of the first COVID-19 vaccines authorized for use in the United States. mRNA vaccines are a new type of vaccine to protect against infectious diseases. They teach the cells of our body to make a protein that triggers an immune response. This immune response leads to the production of antibodies which protects us from getting infected if the real virus enters our body.
We are sitting down with Dr. Drew Weissman, who with his former colleague Katalin Kariko, developed the mRNA technology enabling the creation of the Covid-19 mRNA vaccines, to learn more about the science behind mRNA, the technology and his journey. Dr. Weissman is a professor of Infectious Diseases in Penn’s Perelman School of Medicine and has been working on using RNA in vaccines for more than 15 years.
This talk has been created by CureTalks.com, in association with University of Pennsylvania to facilitate discussions for solutions, with a mission to heal the world through information and sharing of knowledge. At CureTalks we discuss groundbreaking medical research including a wide range of medical, health, and wellness issues, bringing together the doctors, researchers and patients on the same platform.
#mRNAvaccines #Covid19 #coronaviruspandemic
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