At the New York Public Library, the Ghostbusters discover that the Grey Lady (a.k.a the first ghost the Ghostbusters ever encountered) is in possession of a Gozerian Codex and that it would be very useful should Gozer, in fact, be returning. Their investigation into the matter reveals that her name was once Eleanor Twitty and she was the Chief Librarian there at one time. The details of her life are few but it is revealed that she was romantically involved with a gentleman known as "the Collector" because of his acquisition of many rare books. He used Ms. Twitty to gain access to rare materials but when she found out she left him. Enraged, "The Collector" murdered her. Now her spirit is bound to the library to protect the Gozerian Codex from the Collector. The Ghostbusters eventually find Ms. Twitty and capture her- but not without the suspicion that it was far too easy to do so. Their suspicions are confirmed when a "Spirit Door" is revealed, leading into the ghost world. The Ghostbusters travel through the ghost world until they come across the spirit of the Collector, who has taken the form of a giant worm with tendrils protruding from it. After a fierce battle, the Ghostbusters are able to return to the real world. On arriving, they notice that there is some strange marking with 4 lights on the Door, but then one light goes out, indicating to them that whatever it was it must now be turned off. Knowing for certain that there must be something major occurring, the Ghostbusters then rush to the Museum to the get the answers they need to unravel this mystery.
At the Museum the Ghostbusters again find themselves embroiled in a full blown spiritual manifestation (possibly due to certain exhibits having been created by known Gozerian worshipper, doctor and architect, Ivo Shandor). They battle spirits of the various artifacts and spirits with new levels of power- namely, possessing the bodies of the living. Luckily the Ghostbusters have the Slime Blower Mk. II (loaded with the "mood slime" from Ghostbusters II) and are able to use it to dispel the spirits from their human hosts such as the one who had taken the body of Walter Peck. The Ghostbusters again noticed the strange symbol but with time with only two glowing lights on it. Their triumph is short lived, however, because Walter Peck, furious at the damage created and his being hosed down by slime, swears that he's going to revoke the Ghostbusters' license and shut down their containment grid. Again.
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