Restylane Defyne is a hyaluronic acid filler made with XpresHAn technology. It has flexibility, as well as structure making it an ideal product to use in areas of movement, as well as areas that require lifting. I use this product in the cheeks, temples, forehead, nasolabial folds, marionette lines, and jawline. It is one of the most versatile fillers on the market. One of my colleagues called this their “deserted island filler.” If they were stuck on an island and had only one filler to chose, this would be my choice as well. Its G prime is in the mid range, fairly close to that of Voluma. Its duration is similar to most HA fillers, 9-12 months.
